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Fluorescence And Enzyme & Binding Assays Training Courses FLUORESCENCE AND ENZYME & BINDING ASSAYS TRAINING COURSES 21-23 JANUARY PALM SPRINGS, CA, USA For full details visit [Only registered and activated users can see links. Click Here To Register...] Select Biosciences welcomes you to attend training courses run by John C. Owicki PhD, to be held at the Wyndham Hotel, Palm Springs. Dr. Owicki became a consultant in 1999 and is the author of 70 patents and technical papers. He is also on the editorial board of the Journal of Fluorescence. FULL TUTOR BIOGRAPHY: [Only registered and activated users can see links. Click Here To Register...] ------------------------------------------------------- FLUORESCENCE ASSAYS IN DRUG DISCOVERY ------------------------------------------------------- What you could gain by attending: * Master the basic concepts of fluorescence at the level required to understand fluorometric assays and instrumentation. * Become familiar with the application of fluorometric assays to the major classes of pharmacological targets. * Understand the basis and applications of advanced methods such as fluorescence imaging, fluorescence population, time-resolved energy transfer, and fluorescence-fluctuation spectroscopy. * Learn the important types of interferences in fluorometric assays. * Discover where to find more advanced information, using the extensive list of references provided. Topics include: * Fluorescence fundamentals * Labels and labeling chemistries * Instrumentation * Interferences and limitations * Survey of principal fluorescence methods * Biochemical and cellular applications ------------------------------------------------------- ENZYME AND BINDING ASSAYS IN DRUG DISCOVERY ------------------------------------------------------- What you could gain by attending: * Master the basic concepts underlying enzyme and binding assays * Learn how applications in drug discovery sometimes dictate assay optimization and interpretation which differ from textbook recommendations. * Learn how best to extract the information you need from your assays. Topics include: * Enzyme kinetics * Enzyme inhibition: Competitive, noncompetitive, uncompetitive, irreversible, and promiscuous * Multiple-substrate enzymes * Binding equilibria and kinetics * Deviations from classical textbook behavior * Optimizing enzyme and binding assays for primary vs. secondary screening * Understanding mechanisms and extracting information from your data * Discussion of commercial data-analysis and simulation software * Case studies, including receptor binding, kinases, and proteases ------------------------------------------------------- REGISTRATION IS AVAILABLE ONLINE ------------------------------------------------------- [Only registered and activated users can see links. Click Here To Register...] We look forward to seeing you there. best regards aftab ahmad |
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