|Register||Search||Today's Posts||Mark Forums Read|
|Chemistry Forum Chemistry Forum. Discuss chemical reactions, chemistry.|
| ||LinkBack||Thread Tools||Display Modes|
Analysis of cyclobutane pyrimidine dimers
Hi~~ I have some nucleic samples and I believe cyclobutane pyrimidine dimers are present after a certain type treatment. Does anyone know of a method to see the formation of such bondings at an atomic level? Or is there a specific way to check the presence of cyclobutane pyrimidine dimers?
Note: People have been using HPLC-MS/MS for such an application but no protocol has been developed for the type of sample I am using. I might be able to adopt the protocol of a similar type of sample but I doubt the results.
Other possible methods are circular diachroism, NMR, SAXS. All these methods are based on the light absorption or neutron/X-ray reflection/diffraction pattern of the sample, which, to me, is only an indirect readout of the structure of the molecule.
|analysis , cyclobutane , dimers , pyrimidine|
|Thread||Thread Starter||Forum||Replies||Last Post|
|Human Cytome Project - Update 24 Jan. 2005||Peter Van Osta||Cell Biology and Cell Culture||1||08-01-2010 02:18 PM|
|Analysis of Next Generation Sequencing data||Klaus May||Protocols and Methods Forum||0||07-30-2008 09:41 AM|
|Trainings/Projects on Bioinformatics,Molecular Biology,MicroBiology,DrugDesigning and SAS Programming at Global Institute of Biotechnology||Global Institute of Biotechnology||Protocols and Methods Forum||0||11-28-2007 11:31 AM|
|qPCR NEWSLETTER - October 2006||Editor www.Gene-Quantification.info||Protocols and Methods Forum||0||10-26-2006 12:25 PM|
|Sci.chem FAQ - Part 7 of 7||Bruce Hamilton||Chemistry Forum||0||01-15-2004 08:13 AM|