I have troubles to calculate the yield of a peptide synthesis. The point is that I dont understand how I have to use the substitution of the aminoacid in the resin. I will put you one example:
Peptide that I want to synthesize: Lys-Ser-Ala-Wang Resin
Fmoc-Ala-Wang Resin (substitution 0.72 mmol/g)
the goal is to synthesize 0.1 mmol peptide so it means that I have to use 0.139 g of the a.a.-resin (m=0.1mmol peptide/0.72 mmol/g = 0.139g).
So how I have to calculate the theoretical yield?
Thanks for advance