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| dear friends hi! i am relatively new in the site so plz forgive any errors of me!! i have this problem: i am doing a case control study, trying to find if there is a correlation between a bad genotype (7/7) and cancer risk. i must inform you that there are 3 genotypes present: 6/6,6/7 and 7/7 i include 108 patients with cancer and 241 healthy controls. i did x square analysis to find any difference in the contribution of the 3 genotypes and i estimate odds ratio using a 2x2 table analysis. i dont find a significance between the genotype distribution (cases: 35 (6/6), 48 (6/7), 25 (7/7), controls: 111 (6/6), 89 (6/7), 41 (7/7)) i have 2 queries: 1) i cannot estimate the power of my study 2) is my analysis enough or should i do sth in addiction ( addictive model, test for trend?) 3) how can i estimate likelihood ratio for test for trend using SPSS? i would really appreciate if someone could help!!! |
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