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mtDNA question

mtDNA question - Biology Forum

mtDNA question - Biology Forums. Ask questions and discuss the study of Biology. If you have Biology questions from your homework ask them here!


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Old 11-26-2012, 10:57 AM
Pipette Filler
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Default mtDNA question



I have two samples of mtDNA. I need to know, if these two people share the same mother (or at least, descend from the same maternal line). Sequences of HV1 and HV2 showed the following (mutations relate to rCRS):

Person A:
HV1: identical to rCRS
HV2: 263A>G; 315insC

Person B:
HV1: 16354C>T
HV2: 263A>G, 309insCC, 315insC

This result would imo exclude the possibility of sharing the same mother, but I'm not quite sure if the the single point mutation in HV1 and the length difference in the C-stretch of HV2 is enough, or if I would have to call that result "inconclusive".

Anybody with experience: Help please!
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