Nitric Oxide conversion to peroxynitrite
This question is about the effect of peroxynitrite on cell death. Increasing PN production, decreases NO production (NO is scavenged in the process of creating ONOO-). However, the concern/thing that we didnít understand was why PN doesnít instantly kill cells since itís a more potent radical. Sure, you decrease NO, so maybe you get less death that way, but youíre replacing it with something that seems like it would be even worse. So, why do you at least initially get less cell death?
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