I am having an intro course on gen immunology and was preparing an HIV chapter for the exam of gen pathology. I wondered: if HIV targets CD4+ and macrophages, along with few other cell lines, wouldn't the complete chemotherapy-driven depletion of WBCs and a auto-bone marrow transplant be useful? If not, why? one reason I thought of was: nope, because dendritic cells in lymph nodes would keep the virus around for a while, But: after some time has passed in a sterile environment, immune system-free, wouldn't the virus be washed out? I thought a think like this is done for certain leukaemias and other disorders of the immune system, so why not also for HIV?
Thanks for the replies! ^^