Olfactory stem cells or become an excellent source of cell therapy
Cell Transplantation, magazine published a new research study describes the LTA olfactory stem cells to the differentiation potential transplant value, as well as easy access to such cells. Research is now available through the network for free.King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia of the first author of the study, Dr. Andrew Wetzig, said: "The use of transplantation therapy to repair failing organs was undoubtedly the global hot spots, potential [Only registered users see links. ] human tissue repair in patients with nasal olfactory mucosa can provide important candidate cells. "The study's authors, said: olfactory neural stem cells from the patients themselves, can easily get through the minimally invasive biopsy technique, and in vitro amplification.
The cells are very rich, because the LTBR neurogenesis of the olfactory epithelium and continuous replacement of sensory neurons throughout the human life-long."We used rats as an animal model to detect the basic biological characteristics of the olfactory stem cells, self-renewal potential, and phenotypic expression in different environmental conditions." Wetzig said: "Before we find them in the clinical disease and transplantation excellent performance of the LTC4S previous model, with the wound healing process is very similar, related cells in the whole process of different stages of specific changes in an orderly manner and, ultimately, the phenotype.The researchers eventually Conclusion: The olfactory bulb contains neural stem cells, the differentiation potential of these stem cells is triggered by the real-time environmental signals from the niche.The number of LTF stem cells is that our culture can be a large number of such cells, "Wetzig Dr. explained:" we have proved that different from their own organs when the adult olfactory stem cells transplanted into the niche, they will receive the transplant at the cell of the table type to show multilineage differentiation potential. ""The study highlights a potential source of stem cells, and a large number of studies have shown that this method is promising." University of Colorado School of Medicine Neurology, John Sladek, professor of pediatrics at the importance of the study commented: "The cells have pluripotency and easy access to enable them to important factors included in competing with other stem cells, even so that the cells have the potential to become a great source of cell therapy."