Go Back   Science Forums Biology Forum Molecular Biology Forum Physics Chemistry Forum > General Science Forums > Biology Forum
Register Search Today's Posts Mark Forums Read

Biology Forum Biology Forums. Ask questions and discuss the study of Biology. If you have Biology questions from your homework ask them here!


Repair on the chromosome ends

Repair on the chromosome ends - Biology Forum

Repair on the chromosome ends - Biology Forums. Ask questions and discuss the study of Biology. If you have Biology questions from your homework ask them here!


Reply
 
LinkBack Thread Tools Display Modes
  #1  
Old 09-17-2011, 05:36 PM
Pipette Filler
Points: 4, Level: 1 Points: 4, Level: 1 Points: 4, Level: 1
Activity: 0% Activity: 0% Activity: 0%
 
Join Date: Sep 2011
Posts: 1
Thanks: 0
Thanked 0 Times in 0 Posts
Exclamation Repair on the chromosome ends



Dear colleagues!!!

Help me please with some questions in molecular biology.

1. What is the precise length of human RNA-primers in Okazaki fragments? In the literature there are different data from 9 nucleotides to 20 and 30.
2. Precise length of DNA binding sites for such proteins, as: DNA polymerases (all human types), insertase, DNA glycosylases, DNA ligases (I, II, III and IV), RAD51, MRN-complex, and BRCA?
3. Minimal length of oligonucleotide which can be kept on the end of double-stranded DNA in case when the single-stranded break occurs near the chromosome end.

Im interesting in telomere shortening mechanisms and can not find data how the repair occurs on the ends of telomeres and whether it leads to reduction of their length. Anybody know where I can find information about features of DNA damage and repair at the very ends of chromosomes? Whether the repair by homologous recombination can occurs on telomeres as normally recombination events are blocked there by telomeric proteins to prevent activation of ALT mechanism for telomere lengthening?

I shall be very grateful if you write me the links in this field.
Reply With Quote
  #2  
Old 09-24-2011, 04:57 AM
Pipette Filler
Points: 79, Level: 1 Points: 79, Level: 1 Points: 79, Level: 1
Activity: 0% Activity: 0% Activity: 0%
 
Join Date: Sep 2011
Posts: 8
Thanks: 0
Thanked 0 Times in 0 Posts
Default Re: Repair on the chromosome ends

Nice sharing.
I don't have any idea about it because my field is IT.
Sorry again.
Reply With Quote
Reply

Tags
chromosome , ends , repair


Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are On

Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Nobel Goes To Scientists Who Solved How Chromosome Ends Work Urenencesn Science News and Views 3 10-12-2009 01:05 AM
MANUAL CAMERA Brandy Daubenspeck Forum Physik 0 07-14-2009 08:47 PM
An update on tumor suppressor genes in breast cancer (book). scimedweb@mail.com Cell Biology and Cell Culture 0 03-20-2009 10:54 AM


All times are GMT. The time now is 11:35 AM.


Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2014, Jelsoft Enterprises Ltd.
Copyright 2005 - 2012 Molecular Station | All Rights Reserved
Page generated in 0.12154 seconds with 16 queries