Thanks for taking to view and comment on my question My questions centered on human pathogenic protoza specifically gastrointestinal based. There are species that are highly resistant to pharmaceuticals and I have been reading about why this occurs and to gain further understanding.
Assuming that the protozoa are not antigen masking can anyone tell me what other techniques they use to disable pharma drugs. For instance I have been reading about efflux pumps in gram negative bacteria, and I would assume that protozoa use the same mechanism? Secondly would it be safe to assume that their cell membrane provides much of the protection as well?
What I am getting at is if the pharma can penetrate the cell membrane thru a liposomal drug delivery, can the protozoa disable the drug in the cell and by what means.