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Protein structure prediction

Protein structure prediction - Bioinformatics

Protein structure prediction - Have questions about bioinformatic tools or databases? Post questions here. Discuss and post interesting bioinformatics information.


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Old 05-22-2009, 12:26 AM
Pipette Filler
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Default Protein structure prediction



By direct sequencing, I found a polymorphism in the COL4A4 gene (exon 24). It results in a GLU --> GLY substitution. So, how can I predict the change in the protein folding? What´s the first step?
Thanks!
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Old 05-25-2009, 02:07 AM
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Default Re: Protein structure prediction

one thing you can do is to download a PDB file of the COL4A4 gene (if it is available) and use the program PyMol to create the substitution to see the changes in the protein folding.
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