The Comparative Toxicogenomics Database (CTD) elucidates molecular mechanisms by which environmental chemicals affect human disease.
Chemical–gene/protein interactions and chemical– and gene–disease relationships are curated from the published literature, and integrated with diverse data (chemicals, genes/proteins, human diseases, references, sequences, vertebrate and invertebrate organisms, and the Gene Ontology) to facilitate environmental health research.
1.Which human diseases are associated with a gene/protein?
2.Which human diseases are associated with a chemical?
3.Which genes/proteins interact with a chemical?
4.Which chemicals interact with a gene/protein?
5.Which references report a chemical–gene/protein interaction?
6.Which cellular functions (GO terms) are affected by a chemical?