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Islet Inflammation in Autoimmune Diabetes - Type 1 Diabetes Breakthrough

Islet Inflammation in Autoimmune Diabetes - Type 1 Diabetes Breakthrough - Biochemistry Forum

Islet Inflammation in Autoimmune Diabetes - Type 1 Diabetes Breakthrough - Discuss and post questions regarding the study of Biochemistry. If you need homework help this is the place to ask!


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Old 12-16-2006, 11:58 AM
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Cool Islet Inflammation in Autoimmune Diabetes - Type 1 Diabetes Breakthrough



Canada does it again in Diabetes Research!

The team of researchers from Canada discovered that abnormal nerve endings in the insulin-producing cells of the pancreas initiated a chain of events that caused Type 1 diabetes in mice. The removal of these nerve cells blocked the mice from developing Type 1 Diabetes.

Dr. Dosch, a researcher at Sick Children's Hospital et al. identified a control circuit between islet cells and their related sensory nerves. The disruption of this circuit led to inflammation around the islets and eventually to their destruction. Without these cells, the mice could not make insulin.

The article was published yesterday in the Journal Cell

To read the full Article see:
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Cell 2006 127: 1123-1135
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autoimmune , breakthrough , diabetes , inflammation , islet , type


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