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Describe the process of translation. Biochemistry?

Describe the process of translation. Biochemistry? - Biochemistry Forum

Describe the process of translation. Biochemistry? - Discuss and post questions regarding the study of Biochemistry. If you need homework help this is the place to ask!


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Old 06-16-2009, 09:17 PM
Pipette Filler
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Default Describe the process of translation. Biochemistry?



"Translation uses mRNA to direct the synthesis of protein chain. Describe the process of translation. Your answer should include details of the bond breaking, bond making and intermolecular forces involved. 6 marks. "

I have to include tRNA, rRNA, mRNA, condon, anticondon, and peptide bond... We haven't got to know a lot of detail. Still I'm not sure what to put
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Old 06-16-2009, 09:17 PM
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Translation process
The translation process is divided into three steps:

Initiation: When a small subunit of a ribosome charged with a tRNA+the amino acid methionine encounters an mRNA, it attaches and starts to scan for a start signal. When it finds the start sequence AUG, the codon (triplet) for the amino acid methionine, the large subunit joins the small one to form a complete ribosome and the protein synthesis is initiated.

Elongation: A new tRNA+amino acid enters the ribosome, at the next codon downstream of the AUG codon. If its anticodon matches the mRNA codon it basepairs and the ribosome can link the two aminoacids together.(If a tRNA with the wrong anticodon and therefore the wrong amino acid enters the ribosome, it can not basepair with the mRNA and is rejected.) The ribosome then moves one triplet forward and a new tRNA+amino acid can enter the ribosome and the procedure is repeated.



Termination: When the ribosome reaches one of three stop codons, for example UGA, there are no corresponding tRNAs to that sequence. Instead termination proteins bind to the ribosome and stimulate the release of the polypeptide chain (the protein), and the ribosome dissociates from the mRNA. When the ribosome is released from the mRNA, its large and small subunit dissociate. The small subunit can now be loaded with a new tRNA+methionine and start translation once again. Some cells need large quantities of a particular protein. To meet this requirement they make many mRNA copies of the corresponding gene and have many ribosomes working on each mRNA. After translation the protein will usually undergo some further modifications before it becomes fully active.

Diagram in link.
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Old 09-22-2010, 05:42 AM
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Default Re: Describe the process of translation. Biochemistry?

Translation this is where the proteins were produced using the codes of amino acids. Codes for these amino acids are located in the nucleus and must be transferred to proteins ribosomes were made. RNA is only able to implement these data and transmits them to the ribosome. The NRA is just one part of DNA that contain combinations of nucleotides.

Last edited by jasonmark; 09-22-2010 at 05:44 AM.
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