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#1
02-22-2009, 02:14 PM
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 TCA Thermodynamics: calculating ΔG Citrate is formed in an exergonic condensation reaction (ΔG'° = -32.2 kJ/mol) catalyzed by citrate synthase. Imagine your cellular concentrations of reactants and products are the following: oxaloacetate 1 μm; Acetyl CoA 1 μm; Citrate 400 μm; CoA 70 μm. Calculating ΔG for this condition, in which direction does the reaction proceed? If the concentration of all other compounds remained the same, which theoretical concentration of citrate would halt the reaction?  |
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