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conversion ic50 <==> Kd

conversion ic50 <==> Kd - Biochemistry Forum

conversion ic50 <==> Kd - Discuss and post questions regarding the study of Biochemistry. If you need homework help this is the place to ask!


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Old 07-02-2007, 08:00 AM
Pipette Filler
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Default conversion ic50 <==> Kd



hi

can anyone tell me how to convert from a given ic50 (half inhibitory concentration) to a Kd (dissociation constant) unit?
For example i have a MHC complex (HLA B*0801) with a peptide in the binding groove and i know that the ic50 value is around 359.0 for a given peptide FVRQCFNPM. whats the value of the (p)Kd?

thx
lordy

ps sorry for the cross-post but the first time it seems not to be the correct forum
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