Three post-doctoral positions are available in the Medford Lab in the Department of Biology at Colorado State University. Projects include work on the cutting edge field of plant synthetic biology with a focus on synthetic signal transduction, gene circuits for detector plants and sustainable plant-made biofuels.
The Medford lab is one of just a few labs, world-wide, to apply synthetic biology to plants. Synthetic biology allows plant biologists to both probe our understanding of natural systems and re-design or re-wire plants systemsto produce innovative biotechnological tools (see Bowen et al. 2008, Cultivating plant synthetic biology from systems biology. New Phytol. 178: 583-587). One group has defined synthetic biology as "the engineering of biology: the synthesis of complex, biologically based (or inspired) systems, which display functions that do not exist in nature. This engineering perspective may be applied at all levels of the hierarchy of biological structures-from individual molecules to whole cells, tissues and organisms". Examplesof synthetic biology's accomplishments include reprogramming cell morphology, synthetic multi-cellular pattern formation and novel biological functions.
In plants, for example, we have used synthetic biology to produce a synthetic signal transduction system and linked rationally designed components so that input from computationally re-designed receptors produces a highly specific detector plants for substances like environmental pollutants or explosives. The synthetic signal transduction system is being used to dissect complex eukaryotic signaling and is being improved to control biological input and output (e.g., perception and response). Also, using computationally re-designed proteins we have, along with a new biotech company, produced the means to removed unwanted DNA sequences such as antibiotic and herbicide resistance genes from plants.
A Ph.D. in molecular biology, plant molecular biology or a related field isrequired. Ideal applicants will have experience in molecular biology, gene cloning and analysis of transgenic plants. Experience in transgene expression and signal transduction in plant systems as well as skills in written and verbal communication are desirable. The incumbents are expected to interact with other post-docs, graduate students, and part-time undergraduate students. Duties include a variety of molecular biology techniques including synthetic gene construction, bacterial expression, production and analysis of transgenic plants, planning experimental approaches based on research literature, and interpreting results. The successful individuals will be self-motivated and capable of independent thought and research. The positionswill start as soon as possible.
Colorado State University is located in Fort Collins, Colorado a city of 120,000 located at the base of the Rocky Mountains about an hour north of Denver. Colorado boasts 300+ sunny days a year and numerous recreational activities exist from the nearby mountains such as world class skiing and hiking.
Please send your curriculum vitae indicating publications, a brief statement of research experience, and names and telephone numbers of three references to Dr. June Medford via email ([Only registered users see links. ]<mailto:June.Medford@co lostate.edu>). For further information, please contact Dr. Medford.. For full consideration applications must be received by February 27, 2009 by 5 p.m (local time).
Dr. June Medford
Department of Biology
Colorado State University
Fort Collins, CO 80523-1878
Email: [Only registered users see links. ]<mailto:Ju...ol ostate.edu>
Colorado State University is an equal opportunity/affirmative action employer and complies with all federal and Colorado laws, regulations, and executive orders regarding affirmative action requirements in all programs. To assist Colorado State University in meeting its affirmative action responsibilities, ethnic minorities, women and other protected class members are encouraged to apply and to so identify themselves.
Colorado State University is committed to providing a safe and productive learning and living community. To achieve that goal, we conduct background investigations for all final candidates being considered for employment. Background checks may include, but are not limited to, criminal history, national sex offender search and motor vehicle history.