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Postdoctoral positions at The University of British Columbia

Postdoctoral positions at The University of British Columbia - Arabidopsis and Plant Biology

Postdoctoral positions at The University of British Columbia - Discuss Arabidopsis and Plant Biology Research.


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Old 07-03-2008, 10:45 PM
Carl Douglas
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Default Postdoctoral positions at The University of British Columbia



Poplar biofuels: Postdoctoral positions in bioinformatics, genomics,
molecular biology, and biochemistry
University of British Columbia, Vancouver BC, Canada

Six postdoctoral positions in bioinformatics, genomics, molecular biology,
and biochemistry are available as part of a recently funded Genome British
Columbia Applied Genomics Innovation Program (AGIP) project ≥Optimized
Populus feedstocks and novel enzyme systems for a British Columbia bioenergy
sector≤. Positions will be for two to three years, starting in the Fall of
2008, and will be located at the University of British Columbia.

This multi-investigator project is centered at the University of British
Columbia (Departments of Botany, Wood Science, Forest Sciences, the Centre
for Plant Research, and the Michael Smith Laboratories), with collaborators
at the University of Victoria, and the support of technology platforms at
the Vancouver Genome Sciences Centre, Prostate Centre Microarray Facility,
and Centre for Molecular Medicine and Therapeutics (CMMT). International
collaborators include the US Department of Energy, USDA Forest Service, and
Umea Plant Science Center.

If interested, please forward a cover letter indicating the position you
are interested in, a CV, and the names of three references via email with
the subject ≥AGIP Biofuels Position≤ to:

Carl Douglas, Project Leader
AGIP Biofuels
Department of Botany
University of British Columbia
Vancouver BC V6T 1Z4
CANADA
E-mail: [Only registered users see links. ]

Postdoctoral Fellow position - Bioinformatics for population genomics
As part of a team investigating the variation in natural populations of the
completely sequenced model tree Populus trichocarpa (with particular
reference to cellulosic biofuel traits), you will pioneer whole genome SNP
discovery using massive parallel sequencing (Solexa) data. You will
coordinate the assembly of short read data by bioinformatics staff at the
Genome Sciences Centre, Vancouver. You will be responsible, together with
the project database bioinformatician, for pipelining and databasing the
SNPs. You will also be responsible for analytical work on the SNP variation
patterns, including detection of the signature of selection and QTN
detection, and for targeting 6000 SNPs of interest for expanded sampling
using Illumina SNP detection platforms. The position represents a superb
opportunity to work at the leading edge of population genomics and your work
will underpin a major tree biology project. Experience with one or more of
the following would be an advantage: next generation sequencing, short read
assembly, perl programming, database management, statistical genetics, SNP
detection assays and selection detection algorithms.

Postdoctoral Fellow - Massive parallel sequencing, SNP detection and
association genetics.
As part of a team investigating the variation in natural populations of the
completely sequenced model tree Populus trichocarpa (with particular
reference to cellulosic biofuel traits), you will be responsible for the
genome resequencing of trees from natural populations using chip-capture
technology and Solexa sequencing. Your data will be analyzed and pipelined
by bioinformatics colleagues. You will also be responsible for large-scale
SNP assays involving >6000 SNPs and hundreds of trees using the Illumina
Golden Gate system, and in collaborating with phenotypers and
bioinformaticians to perform large scale association analyses with an
extensive range of phenotypic traits. You will have access to
state-of-the-art genomics platforms at the Vancouver Genome Sciences Centre
and at the Centre for Molecular Medicine and Therapeutics. The project
offers the chance to work at the forefront of connecting genome and
phenotype in forest trees. Experience with some or all of the following
would be advantageous: RNA purification, microarray technology, SNP
detection assays, population genetics.

Three Postdoctoral Fellow positions * candidate gene discovery and analysis
As part of a team investigating the variation in natural populations of the
completely sequenced model tree Populus trichocarpa (with particular
reference to cellulosic biofuel traits), you will be responsible for
performing experiments to study Populus candidate genes that may be
important in controlling secondary cell wall development and biochemistry.
You will work with a bioinformatics team and use genome sequence
information, expression profiling data, biological and mutant data, and
phylogenetic analyses to identify candidate genes for further study in
Populus. You will carry our a range of experiments in Populus including
mis-expression in transgenic trees, expression profiling, and study of
recombinant proteins to define the biological roles of these genes in
secondary wall development. Experience in some or all of the following would
be advantageous: molecular biology and genetics, biochemistry, RNA isolation
and qRT-PCR, plant transformation, microarray technology.


Postdoctoral Fellow position * metabolic profiling and secondary cell wall
biochemistry
As part of a team investigating the variation in natural populations of the
completely sequenced model tree Populus trichocarpa (with particular
reference to cellulosic biofuel traits), you will be responsible for
carrying out biochemical and metabolic analyses of the wood and secondary
cell walls from natural and genetically modified Populus variants. This work
will be carried out will the help and collaboration of team members working
on the molecular biology of secondary wall formation in Populus, and
international collaborators. Work will be carried out using state-of-the art
analytical facilities in the Department of Wood Science at UBC. Familiarity
and expertise in analytical biochemistry is required, with expertise in wood
chemistry and metabolic profiling advantageous

Postdoctoral Fellow position * adaptive and biomass trait phenotyping
As part of a team investigating the variation in natural populations of the
completely sequenced model tree Populus trichocarpa (with particular
reference to cellulosic biofuel traits), you will be responsible for
obtaining phenotypic data on physiological traits related to adaptation and
biomass productivity of trees from natural populations, as expressed in
common garden and controlled environment experiments. These data will be
analyzed with respect to the provenance of the genotypes (latitude,
rainfall, elevation) and, in collaboration with other team members, related
to population structure and tested for associations with SNP genotypes of
candidate genes. Experience with some or all of the following would be
advantageous: measurement of A/Ci curves by infra-red gas analysis,
chlorophyll fluorescence, stable carbon and/or nitrogen isotope
discrimination, hydroponics, water relations and frost hardiness assessment..

Postdoctoral Fellow * Wood rot fungi expression profiling
As part of a team investigating the variation in natural populations of the
completely sequenced model tree Populus trichocarpa (with particular
reference to cellulosic biofuel traits), you will be responsible for
carrying out studies on gene expression of wood rot fungi with completely
sequenced genomes using microarray technology. This work will be carried out
collaboratively with partners in the US, with the objective of understanding
the nature of cell wall degrading systems deployed by these fungi, and the
discovery of potential novel enzymes and enzyme complexes that could be
deployed to efficiently de-construct Populus feedstocks of varying wood
chemistry prior to fermentation of released sugars. Experience in some or
all of the following would be advantageous: molecular biology, RNA isolation
and qRT-PCR, transformation, microarray technology, fungal biology.

---------------
Carl J. Douglas
Professor
University of British Columbia
Department of Botany
6270 University Blvd
Vancouver BC V6T 1Z4
Canada

Tel: 1-604-822-2618
Fax: 1-604-822-6089
email: [Only registered users see links. ]



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