A POSTDOCTORAL POSITION is available at the Biotech Center, Rutgers University, in the laboratory of Prof. Eric Lam ([Only registered users see links. ] a highly motivated scientist interested in studying chromatin organization and global regulation of genes via epigenetic control. Recently, we have established a set of about 300 mapped lines of novel transposants in Arabidopsis with single Ds insertions that allows functional and structural characterization of global epigenetic control in living plants. This uniqueresource promises to reveal interesting new insights to the complex network of the epigenome using Arabidopsis as a paradigm. The successful applicant will apply this collection of lines to examine global epigenetic controlas a function of development and in response to stresses. In addition, these lines will also be used to screen for novel chemicals that can regulateepigenetic pathways using chemical biology approach.
The ideal applicant should have prior experience with molecular (ChIP assay, PCR, cloning, northern/Southern blotting, etc.) and biochemical (western blotting, enzyme assay, etc) techniques, advanced microscopy, and/or chemical biology approaches. Knowledge of epigenetic mechanisms is desirable but not required. If you are interested in this position, please email a cover-letter stating your research interests, a curriculum vitae, and contactinformation for three references to: Prof. Eric Lam, [Only registered users see links. ]
The Biotech Center at Rutgers University is located in New Brunswick, New Jersey, and enjoys a convenient location close to the famous Jersey Shore and Pocono Mountains while also easily accessible (within 1 hour by car or train) to metropolitan areas such as New York City and Philadelphia. TheBiotech Center at the School of Environmental and Biological Sciences in the Cook Campus is well-equipped with advanced instrumentations for molecular biology, biochemistry and microscopy. Rutgers University is an equal opportunity employer that strongly encourages underrepresented groups to applyfor open positions.
"Genome-wide transposon tagging reveals location-dependent effects on transcription and chromatin organization in Arabidopsis" Plant J. Published Online: Apr 12 2008; DOI: 10.1111/j.1365-313X.2008.03517.x
“DNA hypomethylation reduces homologous pairing of inserted tandem repeatarrays in somatic nuclei of Arabidopsis thaliana” Plant J. 2005 Nov;44(4):531-40.