using GOtoolBox to analyse sets of Arabidopsis genes

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Dear colleagues,


This short mail to inform the Arabidopsis community of the
availability of GOToolBox, a series of programs using Gene ontology
that we published recently in Genome biology
([Only registered users see links. ]).

GOToolBox can be useful to analyse groups of genes derived from
microarrays,Chromatin-Immunoprecipitations, from the analysis of
protein-protein (two-hybrid), protein_DNA and/or genetic networks,
=2E...

The programs from GOToolBox are directly accessible through a Web
site described in the article.

GOToolBox performs five main tasks:

- gene dataset creation,
- selection and fitting of GO terms at a given ontology level (GO-Diet),
- statistical analysis of GO terms associated with gene sets
(GO-Stats) in order to find over- or under-represented terms,
- GO-based gene clustering (GO-Proxy) allowing to find sub-groups of
functionnally related genes within a gene set,
- gene retrieval based on GO annotation similarity (GO-Family) in
one or several species.

Other developments are presently on their way.

At the moment, GOToolBox supports analyses of GO terms for six species :
Yeast (Sc), Arabidopsis, Drosophila, nematode, mouse and humans.



For the authors,

David Martin and Bernard Jacq

Bernard Jacq
LGPD-IBDM
Parc Scientifique de luminy
13288 Marseille Cedex 9

tel (33) 04 91 82 94 25
fax (33) 04 91 82 06 82


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