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| <x-flowed iso-8859-1>Dear All, I would like to draw your attention to a conference that will be of interest to anybody interested in genetic variation within and between species. The number of attendees is limited, so I urge you to consider registering soon. Keystone Conference on Natural Variation and Quantitative Genetics in Model Organisms Organizers: Detlef Weigel and Bruce Walsh January 8 - 13, 2004 Beaver Run Resort, Breckenridge, Colorado Early Registration Deadline: November 10, 2003 Despite tremendous advances in the genetic analysis of many biological processes, the molecular basis of the variation seen within and between species remains largely unknown. Standard genetic analyses in model organisms have focused on laboratory-induced mutations with large phenotypic effects, which contrasts with the variation seen in natural populations, which is mostly continuous. The phenotypic variation seen within or between closely related species also contrasts with the phenotypic variation seen between more distantly related species. It seems likely, however, that intra- and interspecific variation are two sides of the same coin, although a unifying molecular framework has not yet been developed. Now is an exciting time to revisit these questions because of several major technological advances. These include new analytical tools, such as high-throughput genotyping, new statistical and computational methods, comprehensive transcriptome and proteome profiling, as well as opportunities to compare entire genomes between closely and distantly related organisms. Understanding the molecular basis of natural variation has important implications both for understanding the evolution of new traits, as well as for understanding how selection has shaped genomes, including the human genome. The meeting will have as a major focus both animal and plant model organisms, in which the use of quantitative genetics is experiencing a renaissance. A second focus of the meeting will be recent discoveries of how changes in key regulatory factors cause major phenotypic differences in more distantly related taxa. The overall goal of this meeting is to bring together a diverse group of investigators that includes scientists interested in the evolution of developmental diversity, quantitative geneticists and population geneticists. Finally, the meeting, which will focus on genetic model organisms such as Drosophila and Arabidopsis, will be an excellent complement to the meeting that is to be held concurrently, on Human Genetic Diversity. -- Detlef Weigel, Ph.D. Director Department of Molecular Biology Max Planck Institute for Developmental Biology Spemannstrasse 37-39 D-72076 T=B8bingen Germany Voice +49-(0)179-676 9032 (cell) Voice +49-(0)7071-601 1410 (direct) Voice +49-(0)7071-601 1411 (H=B8lya Wicher, administrative assistant) =46AX +49-(0)7071-601 1409 (direct) or 1412 (administrative assistant) Email [Only registered users see links. ] [Only registered users see links. ] [Only registered users see links. ] --- </x-flowed> |
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| conference , genetic , keystone , natural , variation |
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