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Mitochondrial conditions prior to apoptosis, cell death?

Mitochondrial conditions prior to apoptosis, cell death? - Apoptosis, Autophagy, and Necrosis Forum

Mitochondrial conditions prior to apoptosis, cell death? - Discuss and post questions about Apoptosis, Programmed Cell Death, Necrosis, Autophagy, and other forms of cell death.


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Old 02-17-2014, 01:10 AM
Pipette Filler
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Default Mitochondrial conditions prior to apoptosis, cell death?



A graduate researcher was analyzing a novel intracellular compound in his lab. After
exposing one of his cell cultures to a few micrograms of the compound, he noticed that the
outer membrane of the cellís mitochondria were disrupted and had pores throughout its
surface. However, the inner membrane of all the mitochondria remained completely intact.
Which of the statements is/are true immediately following the outer membrane disruption
prior to cell death?

A. The concentrations of NADH and FADH2 will rapidly decrease within the mitochondria.
B. The concentrations of NADH and FADH2 will rapidly increase within the cytoplasm.
C. The pH within the cytoplasm will increase.
D. The pH within the cytoplasm will decrease.
E. The concentrations of NADH and FADH2 within the mitochondria will remain unchanged.
F. A, B, and D are correct
G. D and E are correct
H. None of the above are correct

Please help me understand this. Thank you!
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apoptosis , cell , conditions , death , mitochondrial , prior


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