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Antibody Forum Antibody Forum. Ask and discuss antibody suppliers, antibody related techniques and protocols, and antibody production such as using phage display libraries.


Hybrid-Human Mouse Monoclonal Antibodies

Hybrid-Human Mouse Monoclonal Antibodies - Antibody Forum

Hybrid-Human Mouse Monoclonal Antibodies - Antibody Forum. Ask and discuss antibody suppliers, antibody related techniques and protocols, and antibody production such as using phage display libraries.


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Old 05-07-2009, 04:43 AM
Pipette Filler
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Default Hybrid-Human Mouse Monoclonal Antibodies



Hi everybody

I want to ask when we want to produce hbrid human - mouse monoclonal antibody, why antigen binding site of mouse is retained instead of human, containing CDR regions of human.Thanks
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Old 05-10-2009, 12:42 PM
Pipette Filler
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Default Re: Hybrid-Human Mouse Monoclonal Antibodies

mouse antibody is a antigen to human body,the hbrid human -mouse monoclonal antibody only contain CDR of mouse antibody,so the antigenicity is smaller,the specificity is the same.
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