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| Animal and Molecular Model Systems Discuss and Post Questions about Animal Model Systems such as Mouse, Rat, Pig, Sheep etc. |
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#1
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| Morpholinos targeting exon 7a of the muscle-specific chloride channel 1 (ClC-1) relieved symptoms of myotonic dystrophy type 1 in two mouse models. Wheeler TM, Lueck JD, Swanson MS, Dirkson RT, Thornton CA. Correction of CIC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy. JCI 2007 doi:10.1172/JCI33355 |
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#2
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| Thanks. Very interesting paper. |
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| blocking , dystrophy , mice , myotonic , splice |
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